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Symbol
Name
ID
S1pr1
sphingosine-1-phosphate receptor 1
MGI:1096355
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal leukocyte migration
abnormal NK cell differentiation
decreased B cell number
decreased NK cell number
increased CD4-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
abnormal lymphocyte physiology
abnormal B cell physiology
decreased susceptibility to experimental autoimmune encephalomyelitis
Availability Mouse Genotype
S1pr1tm1.1Cys/S1pr1tm1.1Cys *
S1pr1tm1.1Thla/S1pr1tm1.1Thla
S1pr1tm1Cys/S1pr1tm1Cys *
S1pr1tm1Rlp/S1pr1tm1Rlp
S1pr1tm1Jch/S1pr1tm1Jch
Tg(Nes-cre)1Kln/0  (conditional)
S1pr1tm1Jch/S1pr1tm1Jch
Tg(Syn1-cre)671Jxm/?  (conditional)
*
S1pr1tm1Jch/S1pr1tm1Jch
Tg(GFAP-cre)25Mes/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory